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David C. Krakauer

“The value (“fitness�) of a given combination of building blocks often cannot be predicted by a summing up of values assigned to the component blocks. This nonlinearity (commonly called epistasis in genetics) leads to co-adapted sets of blocks (alleles) that serve to bias sampling and add additional layers to the hierarchy.”

David C. Krakauer, Worlds Hidden in Plain Sight: The Evolving Idea of Complexity at the Santa Fe Institute, 1984�2019
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