�� Thorough revision of all the chapters without changing basic framework to keep up with the latest changes in the field of medicine.

�� Revision of topics especially respiratory system, immunological factors in disease, diseases of the cardiovascular system, diseases of the gastrointestinal system, acute poisoning and environmental emergencies, oncology, diseases of the kidneys and genitourinary system, diseases due to infections, endocrine and metabolic diseases.

�� Presentation of text pointwise with suitable boxes and tables, which helps the student in quick learning and revision.

�� Addition of newer innovations and treatments modalities.

�� Inclusion of clinical decision pathways for some of the commonly encountered critical and non-emergent disease conditions �� Expansion of normal values of investigations and understanding the evolution of disease.

�� Management of acute medical emergencies like acute myocardial infarction, acute pulmonary oedema, acute anaphylactic and hypovolumic shock, status asthmaticus, tension pneumothorax, status epilepticus, haemoptysis, gastrointestinal bleeding, diabetic coma, snake bites, common poisoning, etc.

�� Emphasis has been laid on clinical presentation with description of the drugs.

New to this Edition

�� Addition of many new line diagrams, tables, flowcharts to facilitate greater retention of knowledge.

�� Updates on Zika, Ebola, Nipah, sepsis, monoclonal antibodies, adult immunisation, paracetamol poisoning, acute radiation syndrome, myelodysplastic syndrome, lymphoid malignancies, influenza, tuberculosis, human immunodeficiency virus infection, hepatitis B and C, heart failure, rheumatic fever, pulmonary hypertension and hyperlipidaemia.

Additional Feature

�� Complimentary access to full e-book

For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease �� it is inevitable.
But what if everything you think you know about ageing is wrong?
What if ageing is a disease? And that disease is curable.
In THE EVOLUTION OF AGEING, Dr. David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that. He has dedicated his life’s work to chasing more than a longer lifespan �� he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick �� a circuit designed to halt reproduction in order to repair damage to the genome –has enabled earth’s early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death.
But genes aren’t our destiny; we have more control over them than we’ve been taught to believe. We can’t change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr. Sinclair will provide a scientifically-proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger longer. Readers will discover how a few simple lifestyle changes �� like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy �� can activate our vitality genes. Dr. Sinclair ends the book with a look to the near future, exploring what the world might look like �� and what will need to change �� when we are all living well to 120 or more.
Dr. Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. THE EVOLUTION OF AGEING is destined to be the biggest book on genes, biology, and longevity of this decade.